酶科学/TNF-R1（人）单克隆抗体（H398）/ALX-804-200-C100/100µ；G
商品编号：
ALX-804-200-C100
品牌：
enzolifesciences
市场价：
¥6320.00
美元价：
3792.00
产品分类：
特色ELISA试剂盒
公司分类：
Specialty_ELISA_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
ProductSpecification:
| AlternativeName: | TNF-R60kDa,CD120a,p55,TNFRSF1A |
| Clone: | H398 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | HumanTNF-R1. |
| UniProtID: | P19438 |
| Speciesreactivity: | Human |
| Specificity: | Recognizesmembrane-boundandsolubleTNF-R1. |
| Crossreactivity: | Doesnotcross-reactwithmouseTNF-R1. |
| Applications: | FlowCytometry,IHC(FS),FUNC |
| RecommendedDilutions/Conditions: | Immunohistochemistry(frozensections;stainsacetone-fixedcryostatsectionsorcellsmears.RecommendedforH398isthealkalinephosphatase-anti-alkaline-phosphatase(APAAP) orperoxidaseanti-peroxidase(PAP)proceduresorthethreestageimmunoperoxidasetechniqueonacetone-fixedcryostatsections.H398maybeusedataconcentrationof1-0.5mg/mlforcryostatsections) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| ApplicationNotes: | NotrecommendedforIHC(PS). FunctionalApplication:blocksTNF-Rsignalling.10µg/mlH398neutralizesTNFinducedcytotoxicityonU937(100%).FurThermore,10µg/mlH398neutralizesTNFinducedMHCexpressiononK562,Colo205andIL2RonYTcells(always100%). TNFinducedcytotoxicitycanbeinhibited/neutralizedbyH398onMCF-7,HeLaandL929.Aworkingconcentrationcouldnotbedetermined,sinceascitesantibodypreparationshavebeenusedwhichexhibitanunspecificcytotoxiceffectonthecells.FunctionalactivityviatheTNF-R1iscompletelyinhibitedbyH398althoughonsomecellstheligandstillbinds.Thus,theantibodyH398inhibitssignallingviathereceptorbutnotalwaysthebindingofTNF. |
| PurityDetail: | ProteinGaffinitypurified. |
| Formulation: | Liquid.InPBS. |
| Handling: | Avoidfreeze/thawcycles.Afteropening,preparealiquotsandstoreat-20°C. |
| Shipping: | ShippedonBlueIce |
| LongTermStorage: | +4°C |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
Our breadth of scientific expertise coupled with unique technology platforms give us the flexibility to drive innovation throughout the entire research continuum. From life sciences research discovery efforts, through drug development, and into clinical research, our comprehensive range of products are designed to support your goals. When a standard catalog product does not meet your needs, talk to us about custom solutions; we can help
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