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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/RBP4 polyclonal antibody/ALX-210-974-0100/100µg
商品详细Enzolifesciences/RBP4 polyclonal antibody/ALX-210-974-0100/100µg
Enzolifesciences/RBP4 polyclonal antibody/ALX-210-974-0100/100µg
Enzolifesciences/RBP4 polyclonal antibody/ALX-210-974-0100/100µg
商品编号: ALX-210-974-0100
品牌: enzolifesciences
市场价: ¥8420.00
美元价: 5052.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:Retinol binding protein 4
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 245-350 of human RBP4.
 
UniProt ID:P02753 (human), P04916 (rat), Q00724 (mouse)
 
Species reactivity:Human, Mouse, Rat
Bovine, Chicken, Dog, Horse, Porcine
 
Applications:ELISA, ICC, IF, IHC (FS), IHC (PS), IP, WB
 
Recommended Dilutions/Conditions:ELISA (1:500-1:1,000)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (frozen and paraffin sections, 1:100-1:500)
Immunoprecipitation (1:20-1:100)
Western Blot (1:100-1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~23kDa by Western blot.
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In 10mM PBS, pH 7.4, containing 10mg/ml BSA and 0.1% sodium azide.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:RBP4 (retinol binding protein 4) belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. Clinically, RBP4 has recently been described as an adipokine that contributes to insulin resistance in the AG4KO mouse model.  It is secreted by adipocytes, and can act as a signal to other cells, when there is a decrease in plasma glucose concentration.
 
品牌介绍
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