当前位置：
首页
>
产品中心 >
exosome_research >
Enzolifesciences/Proliferating cell nuclear antigen monoclonal antibody (PC10)/ALX-801-091-L001/1ml
Enzolifesciences/Proliferating cell nuclear antigen monoclonal antibody (PC10)/ALX-801-091-L001/1ml
商品编号：
ALX-801-091-L001
品牌：
enzolifesciences
市场价：
¥13160.00
美元价：
7896.00
产品分类：
外泌体研究
公司分类：
exosome_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product Specification:
| Alternative Name: | PCNA |
| Clone: | PC10 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | Recombinant rat PCNA (proliferating cell nuclear antigen). |
| UniProt ID: | P04961 |
| Species reactivity: | Insect, Schizosaccharomyces pombe, Vertebrate |
| Specificity: | Intense nuclear staining of proliferating cells in normal and tumor tissues. |
| Applications: | IHC (PS) |
| Recommended Dilutions/Conditions: | Immunohistochemistry (paraffin sections): Can be used for formalin-fixed, paraffin-embedded tissues. Pretreatment is not required. Recommended dilution is ≥1:40 for biotin based detection. For optimal staining, incubate 20-60 min. at room temperature. Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually. |
| Positive Control: | Human colon or tonsil can be used as positive control. |
| Formulation: | Liquid. In 0.01M PBS containing 0.1% sodium azide and 1% BSA. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Short Term Storage: | +4°C |
| Long Term Storage: | -20°C |
| Scientific Background: | Proliferating Cell Nuclear Antigen (PCNA) is associated with the DNA replication fork and its major function is described as a processivity factor for replicative DNA polymerases (polymerases δ and ε ) acting as a sliding clamp. It has a highly conserved amino acid sequence and has been identified in all eukaryotes and is being used as a proliferating marker. PCNA is also able to interact with multiple partners involved in Okazaki fragment joining, DNA repair, DNA methylation and chromatin assembly. In DNA repair PCNA has been reported not only for nucleotide excision repair (NER) (in concert with XPG and ERCC1), but also for base excision repair (BER) (binding to uracil-DNA glycosylase) and mismatch repair (MMR) (binding to mismatch repair enzymes MSH2 & MLH1). It is further associated with cell cycle control through cdk-cyclins during G1 to S phase. |
品牌介绍
Product categoriesPharmaceuticals And Biochemic
CAS 6090-98-8
conduritol F
CAS 20544-37-0
2,4,8,10-Tetraoxa-3,
CAS 135564-23-7
Benzaldehyde, 4-amin
CAS 34169-62-5
2-Naphthalenesulfoni
CAS 6305-52-8
2-Butyldecahydronaph
CAS 10074-13-2
1,3-Benzenedimethane
CAS 84434-05-9
Acetic acid,2-[(9-ox
CAS 104748-51-8
Avilamycin K
CAS 5539-08-2
Ergoline-8-carboxyli
CAS 1242-56-4
Androst-1-en-3-one,1
CAS 52978-30-0
(1R,2R,3E,5E,15E,17E
CAS 24471-48-5
2-Pyrenemethanol
CAS 39325-01-4
Picibanil
CAS 244290-68-4
Quinolinium, 7-[(die
CAS 80584-90-3
1H-Benzotriazole-1-m
CAS 65193-87-5
Butanoic acid, 3-oxo
CAS 3563-92-6
Zylofuramine
CAS 24979-74-6
Phenol,4-ethenyl-, p
CAS 1067-48-7
1-Pentanamine, 5-(tr
CAS 62886-59-3
Sephadex-CM C-25,ion
View all products
Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
Our breadth of scientific expertise coupled with unique technology platforms give us the flexibility to drive innovation throughout the entire research continuum. From life sciences research discovery efforts, through drug development, and into clinical research, our comprehensive range of products are designed to support your goals. When a standard catalog product does not meet your needs, talk to us about custom solutions; we can help
品牌分类
抗体
联络我们
