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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/PGE2 polyclonal antibody/ADI-905-025-1/1ml
商品详细Enzolifesciences/PGE2 polyclonal antibody/ADI-905-025-1/1ml
Enzolifesciences/PGE2 polyclonal antibody/ADI-905-025-1/1ml
Enzolifesciences/PGE2 polyclonal antibody/ADI-905-025-1/1ml
商品编号: ADI-905-025-1
品牌: enzolifesciences
市场价: ¥2940.00
美元价: 1764.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:Prostaglandin E2
 
Host:Rabbit
 
Immunogen:Prostaglandin E2.
 
Species reactivity:Species independent
 
Applications:ELISA
Radioimmunoassay
 
Formulation:Liquid. In phosphate buffer containing bovine gamma globulin and 0.1% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and sepsis. Oxidation of arachidonic acid by prostaglandin synthases (COX-1 and COX-2) produces prostaglandin H2 (PGH2), which is further metabolized by PGE synthases into its major product, PGE2. PGE2 mediates autocrine and paracrine signaling by binding to G-protein coupled receptors (EP1, EP2, EP3, EP4) on the cell surface, functioning to modulate phospholipase C and adenylate cyclase activity. PGE2 has been of great interest as a therapeutic target, either by modulation of its synthesis by COX inhibitors (NSAIDS) or by modulation of its receptors by downregulation or binding antagonists. PGE2 production in a variety of tissues has been shown to modulate numerous physiological processes including natriuresis in the kidney, smooth muscle elasticity in the vasculature, and the inflammatory response to damaged tissues by monocytes and macrophages.
 
品牌介绍
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