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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/Notch1 monoclonal antibody (3E12)/ADI-905-897-100/100µl
商品详细Enzolifesciences/Notch1 monoclonal antibody (3E12)/ADI-905-897-100/100µl
Enzolifesciences/Notch1 monoclonal antibody (3E12)/ADI-905-897-100/100µl
Enzolifesciences/Notch1 monoclonal antibody (3E12)/ADI-905-897-100/100µl
商品编号: ADI-905-897-100
品牌: enzolifesciences
市场价: ¥8520.00
美元价: 5112.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Clone:3E12
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Recombinant human Notch1 (aa 2300-2556).
 
UniProt ID:P46531
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~280kDa (full length) by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Notch1 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.
 
品牌介绍
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