酶学/毒蕈碱受体M1多克隆抗体/ADI-905-796-100/100µ；G
商品编号：
ADI-905-796-100
品牌：
enzolifesciences
市场价：
¥5720.00
美元价：
3432.00
产品分类：
外泌体研究
公司分类：
exosome_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product Specification:
| Alternative Name: | Acetylcholine muscarinic receptor 1, Cholinergic muscarinic receptor 1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of rat muscarine receptor M1. |
| UniProt ID: | P04761 |
| Species reactivity: | Rat |
| Crossreactivity: | Predicted species reactivity based on epitope sequence homology: human, mouse, horse, bovine, guinea pig, dog, orangutan, chimpanzee, wild boar, rhesus macaque, opossum. |
| Applications: | WB |
| Application Notes: | Predicted MW of ~51kDa. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 50% glycerol and 0.01% sodium azide. |
| Handling: | Keep on ice at all times. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The pharmacologic activity of acetylcholine (ACTH) is mediated by the ionotropic nicotinic receptor or via metabotropic muscarinic receptors. Five known acetylcholine (muscarinic) receptors (M1-M5) are variably expressed in the central nervous system and periphery, mediating motor control, thermoregulation, memory, smooth muscle contraction, glandular secretion, and cardiac function. Although the physiology of the five mammalian muscarinic receptor homologs does not differ significantly in their affinities to a variety of agonists (ACTH, muscarine) and antagonists (e.g., atropine), they can be divided into two sub-groups (M1/M3/M5 and M2/M4) based on G alpha subunit coupling preferences. M1/M3/M5 receptors signal primarily via Gq/11 alpha subunits to stimulate phospholipase C, whereas M2/M4 receptors couple to Gi/o alpha subunits to inhibit adenylyl cyclases and cAMP production. Modulation of muscarinic receptor activity holds promise for the treatment of psychiatric and neurological disorders including schizophrenia and Alzheimer's disease. |
| Manufacturer: | Manufactured by Proteimax. |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
Our breadth of scientific expertise coupled with unique technology platforms give us the flexibility to drive innovation throughout the entire research continuum. From life sciences research discovery efforts, through drug development, and into clinical research, our comprehensive range of products are designed to support your goals. When a standard catalog product does not meet your needs, talk to us about custom solutions; we can help
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