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Enzolifesciences/Matrix Gla protein monoclonal antibody (52.1#1)/ENZ-ABS254-0050/50µg
Enzolifesciences/Matrix Gla protein monoclonal antibody (52.1#1)/ENZ-ABS254-0050/50µg
商品编号:
ENZ-ABS254-0050
品牌:
enzolifesciences
市场价:
¥0.00
美元价:
0.00
产品分类:
外泌体研究
公司分类:
exosome_research
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Specification:
Alternative Name: | MGP |
Clone: | 52.1#1 |
Host: | Mouse |
Isotype: | IgG1 |
Immunogen: | Synthetic peptide corresponding to aa 3-15 of non-phosphorylated human MGP (matrix Gla protein). |
UniProt ID: | P08493 |
Species reactivity: | Human |
Specificity: | Recognizes both carboxylated and non-carboxylated human matrix Gla protein. |
Crossreactivity: | Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset (100%); Dog, Horse, Rabbit (92%); Mouse, Rat, Bovine, Bat, Pig, Opossum (85%). |
Applications: | IF, IHC (PS), IP, WB |
Recommended Dilutions/Conditions: | Immunofluorescence (1:50-1:500) Immunohistochemistry (paraffin sections, 1:50-1:500) Immunoprecipitation (1-2 μg per 100-500 μg) Western Blot (1:200-1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
Formulation: | Liquid. In 0.5 ml PBS containing < 0.1% sodium azide and 0.1% gelatin. |
Use/Stability: | Stable for 1 year when stored at +4°C. |
Handling: | Do not freeze. |
Shipping: | Blue Ice Not Frozen |
Short Term Storage: | +4°C |
Long Term Storage: | +4°C |
Scientific Background: | Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification. MGP is mainly synthesized and expressed in cartilage and the vessel wall, where it is produced by the chondrocytes and vascular smooth muscle cells, respectively. During biosynthesis, MGP undergoes two forms of post-translational modifications: the phosphorylation of 3 serine residues and the γ-carboxylation of 5 glutamate residues. Phosphorylation of MGP is essential for its regular cellular secretion, and the vitamin K-dependent carboxylation is crucial for the calcification inhibitory activity. MGP plays a role in bone metabolism and atherosclerosis. |
品牌介绍
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
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