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Enzolifesciences/LTB4 receptor (BLT1) polyclonal antibody/ADI-905-793-100/100µg
Enzolifesciences/LTB4 receptor (BLT1) polyclonal antibody/ADI-905-793-100/100µg
商品编号：
ADI-905-793-100
品牌：
enzolifesciences
市场价：
¥5920.00
美元价：
3552.00
产品分类：
外泌体研究
公司分类：
exosome_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product Specification:
| Alternative Name: | Leukotriene B4 Receptor 1, LTB4-R1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of rat LTB4 Receptor (BLT1). |
| UniProt ID: | Q9R0Q2 |
| Species reactivity: | Rat |
| Crossreactivity: | Predicted species reactivity based on epitope sequence homology: mouse. |
| Applications: | WB |
| Application Notes: | Predicted MW of ~38kDa. Higher MW species (~50kDa) also observed by Western blot which reflect post-translational modification of the receptor. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 50% glycerol and 0.01% sodium azide. |
| Handling: | Keep on ice at all times. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Leukotrienes are metabolic products of arachidonic acid formed by the action of 5-lipoxygenase (5-LO), with the principal products being leukotrienes C4 (LTC4) and B4 (LTB4). LTB4 is a dihydroxy-leukotriene produced in a variety of cells including eosinophils, neutrophils, platelets, and vascular cells, and is a potent leukocyte chemoattractant known to regulate leukocyte activation, cytokine secretion, inflammatory gene transcription, and IgE synthesis. As such, LTB4 has been implicated in a number of disease pathologies including atherosclerosis, asthma, psoriasis, and inflammatory bowel disease. The many actions of LTB4 are associated with two identified mammalian receptors, BLT1 and BLT2. BLT1 is a high-affinity LTB4 receptor expressed on peripheral leukocytes, while BLT2 is a more ubiquitously expressed low affinity LTB4 receptor whose function is not well understood. The BLT1 receptor is transiently expressed by antigen-primed T-cells in humans, and its expression is known to play a critical role in collagen-induced arthritis in mice. |
| Manufacturer: | Manufactured by Proteimax. |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
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