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Enzolifesciences/IL-13 receptor (human) monoclonal antibody (GM-1C8)/ALX-804-506-C100/100µg
Enzolifesciences/IL-13 receptor (human) monoclonal antibody (GM-1C8)/ALX-804-506-C100/100µg
商品编号：
ALX-804-506-C100
品牌：
enzolifesciences
市场价：
¥7020.00
美元价：
4212.00
产品分类：
外泌体研究
公司分类：
exosome_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product Specification:
| Alternative Name: | IL-13R, CD213, Interleukin-13 receptor |
| Clone: | GM-1C8 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Vector containing the cDNA of the extracellular domain of human IL-13Rα1 (interleukin-13 receptor α1 chain). |
| UniProt ID: | P78552 (subunit α1), Q14627 (subunit α2) |
| Source: | Purified by affinity chromatography from cell culture supernatant. |
| Species reactivity: | Human |
| Applications: | Flow Cytometry |
| Quality Control: | Routinely tested by flow cytometry on BOSC cells transiently transfected with a IL-13Rα1 expression vector. |
| Formulation: | Liquid. Antibody in PBS, pH 7.2, containing 0.01% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Short Term Storage: | +4°C |
| Long Term Storage: | -20°C |
| Scientific Background: | IL-13 is an immunoregulatory cytokine secreted predominantly by activated TH2 cells, as well as mast cells and basophils, and is a key mediator in the pathogenesis of allergic inflammation. The human IL-13 receptor (IL-13R) is a heterodimer composed of the interleukin-4 receptor a chain (IL-4Rα) and an IL-13 binding protein, IL-13Rα1.A second IL-13 binding protein, IL-13Rα2, has also been identified, which is believed to act as a "decoy" receptor. IL-13 receptors are expressed on human B cells, basophils, eosinophils, mast cells, endothelial cells, fibroblasts, monocytes, macrophages, respiratory epithelial cells, and smooth muscle cells. However, functional IL-13 receptors have not been demonstrated on human or mouse T cells. As with other cytokine receptors, the cytoplasmic tails of IL-4 and IL-13 receptor subunits associate with tyrosine kinases of the Janus family (JAK 1 |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
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