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Enzolifesciences/5-Hydroxymethylcytosine polyclonal antibody/ADI-905-904-0200/200µg
Enzolifesciences/5-Hydroxymethylcytosine polyclonal antibody/ADI-905-904-0200/200µg
商品编号：
ADI-905-904-0200
品牌：
enzolifesciences
市场价：
¥12680.00
美元价：
7608.00
产品分类：
外泌体研究
公司分类：
exosome_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product Specification:
| Alternative Name: | 5-hmC |
| Host: | Rabbit |
| Isotype: | IgG1 |
| Immunogen: | 5-Hydroxymethylcytosine |
| Species reactivity: | Species independent |
| Specificity: | Recognizes 5-hydroxymethylcytosine in single-stranded DNA from any mammalian, plant, insect, or microbial sources, as well as artificial templates used for standardization. |
| Applications: | ELISA, IP Immunoblot |
| Recommended Dilutions/Conditions: | ELISA (1:1,000-5,000) Immunoblotting (Dot blotting, 1:500-2,000) Immunoprecipitation (1-2 µg). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Purified. |
| Formulation: | Liquid. In PBS, pH 7.5, containing 0.05% sodium azide. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Recent advances in the field of epigenetics have identified 5-hydroxymethylcytosine (5-hmC) as a key factor in the regulation of gene expression, with substantial implications in the study of tissue differentiation, neurological development, and carcinogenesis. Studies of this epigenetic marker are typically confounded by a lack of reliable methodology for differentiation from the highly prevalent 5-methylcytosine in a DNA sample. The 5-hydroxymethylcytosine pAb has been developed in order to robustly distinguish between hydroxymethylated DNA and methylated or unmodified DNA. Specificity of the antibody is enhanced such that crossreactivity with unmodified and methylated templates is suppressed to near-background levels. The antibody has been extensively tested and validated in ELISA and immunoprecipitation-based enrichment assays, and is suitable for use in further applications including immunohistochemical labeling and chromatographic blotting. Overall, the 5-hydroxymethylcytosine pAb has low cross reactivity with cytosine and 5-methylcytosine versus other available antibodies; can be used with a variety of genomic DNA sources; and has high sensitivity to low masses of 5-hydroxymethylcytosine DNA. |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
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