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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/HSP40/Hdj1 monoclonal antibody (2E1)/ADI-SPA-450-E/100µg
商品详细Enzolifesciences/HSP40/Hdj1 monoclonal antibody (2E1)/ADI-SPA-450-E/100µg
Enzolifesciences/HSP40/Hdj1 monoclonal antibody (2E1)/ADI-SPA-450-E/100µg
Enzolifesciences/HSP40/Hdj1 monoclonal antibody (2E1)/ADI-SPA-450-E/100µg
商品编号: ADI-SPA-450-E
品牌: enzolifesciences
市场价: ¥6320.00
美元价: 3792.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:Heat shock protein 40
 
Clone:2E1
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Recombinant human Hsp40 (Hdj1).
 
UniProt ID:P25685
 
GenBank ID:D49547
 
Species reactivity:Human, Mouse, Rat
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (2-5µg/200µl from 5x106cells)
Western Blot (1-2µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~40kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.
 
品牌介绍
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