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当前位置: 首页 > 产品中心 > exosome_research > 酶科学/Herc5(人)多克隆抗体/BML-PW0920-0100/100µ;L
商品详细酶科学/Herc5(人)多克隆抗体/BML-PW0920-0100/100µ;L
酶科学/Herc5(人)多克隆抗体/BML-PW0920-0100/100µ;L
酶科学/Herc5(人)多克隆抗体/BML-PW0920-0100/100µ;L
商品编号: BML-PW0920-0100
品牌: enzolifesciences
市场价: ¥7480.00
美元价: 4488.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:HECT domain and RCC1-like domain-containing protein 5, Cyclin-E-binding protein 1, CEBP1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to amino acid residues 402-414 of human Herc5.
 
UniProt ID:Q9UII4
 
Species reactivity:Human
 
Crossreactivity:Does not cross-react with Herc6.
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Partially purified by salt precipitation.
 
Formulation:Liquid. In PBS containing 0.01% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:ISG15 is an interferon-induced and antiviral ubiquitin-like protein (Ubl). The ability of ISG15 to be conjugated to other proteins has been shown in some cases to be essential for its antiviral activity. Herc5 (HECT domain and RCC1-like domain-containing protein 5), the major E3 enzyme for ISG15, mediates the ISGylation of more than 300 proteins in interferon-stimulated cells. Herc5 is thought to broadly modify newly synthesized proteins in a co-translational manner, suggesting that, in the context of an interferon-stimulated cell, newly translated viral proteins may be primary targets of ISG15. The biochemical function of ISG15 conjugation and the basis of the antiviral activities of ISG15 conjugation have yet to be fully elucidated.
 
Technical Info/Product Notes:BML-PW0920 has been characterized extensively by Western blotting of Herc5 transfected 293T cell lysate and IFN-stimulated 293T, HeLa and A549 cell lysates.
 
品牌介绍
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