酶学/醇溶蛋白肽单克隆抗体(14D5)/BPD-HYB-314-01-02/200µ;G
商品编号:
BPD-HYB-314-01-02
品牌:
enzolifesciences
市场价:
¥8720.00
美元价:
5232.00
产品分类:
外泌体研究
公司分类:
exosome_research
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Specification:
Alternative Name: | alpha Gliadin |
Clone: | 14D5 |
Host: | Mouse |
Isotype: | IgG2aλ |
Immunogen: | Synthetic peptide corresponding to aa Lys57-Glu65-[α-gliadin (58-73)] (KLQPFPQPELPYPQPQ) of Gliadin-related peptide. |
Species reactivity: | Plant |
Applications: | ELISA, WB |
Application Notes: | Detects a band of ~6 to 10kDa by Western blot. |
Purity Detail: | Protein A/G-affinity purified. |
Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
Shipping: | Blue Ice Not Frozen |
Short Term Storage: | +4°C |
Scientific Background: | Celiac disease is associated with a CD4+ T-cell response to epitopes of gliadin presented by HLA-DQ2 or -DQ8 class II MHC molecules. These epitopes are present in a 33-mer peptide of wheat alpha-gliadin, residues 56-88, which is resistant to digestion and forms a substrate for tissue transglutaminase (TG2), generating the glutamic acid residues essential for binding to HLA-DQ2. The immunogen corresponds to a deamidated form of a region that includes the T-cell epitopes, including the immunodominant PQPQLPY region and two PXPQP motifs associated with binding to IgA from patients with celiac disease. Complete homology exists between residues 63-73, 70-80 and 77-87 of wheat alpha gliadin. |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
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