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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/Diglycyl Lysine monoclonal antibody (GX41)/ADI-908-310-0100/100µg
商品详细Enzolifesciences/Diglycyl Lysine monoclonal antibody (GX41)/ADI-908-310-0100/100µg
Enzolifesciences/Diglycyl Lysine monoclonal antibody (GX41)/ADI-908-310-0100/100µg
Enzolifesciences/Diglycyl Lysine monoclonal antibody (GX41)/ADI-908-310-0100/100µg
商品编号: ADI-908-310-0100
品牌: enzolifesciences
市场价: ¥4940.00
美元价: 2964.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Clone:GX41
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Diglycine-modified histone from calf thymus, Type III-S, lysine rich fraction.
 
Species reactivity:Species independent
 
Specificity:Recognizes diglycyl modified lysine, a ubiquitin remnant detectable after trypsin digestion.
 
Applications:IP, WB
 
Purity Detail:Protein G purified.
 
Formulation:Liquid. In PBS containing 0.1% sodium azide.
 
Handling:Store unopened vial at -20°C until required for use. Store diluted antibody at 2-4°C and use within 1 month. Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein ubiquitination is a fundamentally important post-translational modification that regulates myriad cell signaling pathways in eukaryotes. Alterations in protein ubiquitination have been linked to cancers and neurodegenerative, cardiovascular, immunological, and inflammatory diseases.

Identification of exact ubiquitinylation sites is challenging under physiological conditions, but the recent development of an immunoprecipitation approach allows for enrichment and identification of peptides derived from the ubiquitinated portion of proteins.

When ubiquitinated protein is digested with trypsin a diglycine residue remains at any lysine site of ubiquitin attachment. Diglycyl Lysine, mAb (GX41) facilitates easy capture and enrichment of peptides derived from ubiquitinated proteins by recognizing the diglycyl-lysine residue with no detectable reactivity to non modified lysines.
 
品牌介绍
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