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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/Cytochrome P450 2E1 polyclonal antibody/BML-CR3271-0100/100µl
商品详细Enzolifesciences/Cytochrome P450 2E1 polyclonal antibody/BML-CR3271-0100/100µl
Enzolifesciences/Cytochrome P450 2E1 polyclonal antibody/BML-CR3271-0100/100µl
Enzolifesciences/Cytochrome P450 2E1 polyclonal antibody/BML-CR3271-0100/100µl
商品编号: BML-CR3271-0100
品牌: enzolifesciences
市场价: ¥7740.00
美元价: 4644.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:CYP2E1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the C-terminus of hepatic human, rat, rabbit, and mouse CYP2E1.
 
UniProt ID:P05181 (human), P05181 (mouse), P05182 (rat), P08682 (rabbit)
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC (FS), IHC (PS), WB
 
Recommended Dilutions/Conditions:The antiserum detects CYP2E1 in rat liver microsomal preparations and in rat brain by Western blotting (~57kDa) and in immunohistochemical applications at a dilution of 1:1000 or greater when using sensitive detection methods. Such as enhanced chemiluminescence (ECL; Amersham) for Western blotting applications, and ABC-Elite (Vector Laboratories) for immunohistochemistry. The use of 2-4% neutral-buffered formaldehyde or methacarn fixation is recommended. Frozen sections are recommended, but dewaxed tissue sections have also been used satisfactorily. Antigen retrieval techniques may enhance signal generation.

Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~57kDa by Western blot.
 
Blocking Peptide:For Blocking peptide see Prod. No. BML-CP0270.
 
Formulation:Rabbit antiserum. Contains no preservatives.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cytochrome P-450 2E1(CYP2E1) is principally found in the liver, and is ethanol-inducible. It catalyzes many biotransformations. In rat brain CYP2E1 is localized to cells within the substantia nigra and in striatial blood vessels where a possible role in the pathology of oxidative stress, believed to underlie nigral degeneration has been proposed. Recently, increased expression of human CYP2E1 mRNA, along with that of several other CYP genes, has been found in the uterine endometrium of patients treated with tamoxifen.
 
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