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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/CD8 (α chain) Recombinant monoclonal antibody (C8/1779R)/ENZ-ABS323-0100/100µg
商品详细Enzolifesciences/CD8 (α chain) Recombinant monoclonal antibody (C8/1779R)/ENZ-ABS323-0100/100µg
Enzolifesciences/CD8 (α chain) Recombinant monoclonal antibody (C8/1779R)/ENZ-ABS323-0100/100µg
Enzolifesciences/CD8 (α chain) Recombinant monoclonal antibody (C8/1779R)/ENZ-ABS323-0100/100µg
商品编号: ENZ-ABS323-0100
品牌: enzolifesciences
市场价: ¥9680.00
美元价: 5808.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:T-cell surface glycoprotein CD8 (α chain), T-lymphocyted differentiation antigen T8/Leu-2
 
Clone:C8/1779R
 
Host:Rabbit
 
Isotype:IgGκ
 
Immunogen:Recombinant full length human CD8a.
 
UniProt ID:P01732
 
Species reactivity:Human
 
Applications:Flow Cytometry, IF, IHC (PS)
 
Recommended Dilutions/Conditions:Flow Cytometry (0.5-1 µg/106 cells
Immunofluorescence (0.5-1 µg/mL)
Immunohistochemistry (formalin-fixed paraffin sections) (0.5-1 µg/mL for 30 min at RT)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α/β) or as a homodimer (CD8 α/α). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
 
品牌介绍
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