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当前位置: 首页 > 产品中心 > exosome_research > Enzolifesciences/Calreticulin monoclonal antibody (FMC 75)/ADI-SPA-601-D/50µg
商品详细Enzolifesciences/Calreticulin monoclonal antibody (FMC 75)/ADI-SPA-601-D/50µg
Enzolifesciences/Calreticulin monoclonal antibody (FMC 75)/ADI-SPA-601-D/50µg
Enzolifesciences/Calreticulin monoclonal antibody (FMC 75)/ADI-SPA-601-D/50µg
商品编号: ADI-SPA-601-D
品牌: enzolifesciences
市场价: ¥4320.00
美元价: 2592.00
产地: 美国(厂家直采)
公司:
产品分类: 外泌体研究
公司分类: exosome_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product Specification:

Alternative Name:CALR, CRT
 
Clone:FMC 75
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant calreticulin.
 
UniProt ID:P27797 (human)
 
Species reactivity:Human
Monkey
 
Applications:ICC, IHC (PS), IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (12.5µg/ml)
Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Predicted MW of ~63kDa.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Calreticulin (CRT) is a multifunctional, multi-compartmental protein most abundant in the ER lumen. CRT contains the ER-retrieval sequence, KDEL, and has been best characterized as a soluble molecular chaperone of new or misfolded proteins and a Ca2+- binding protein. Both CRT and its membrane bound homolog, Calnexin (CNX) interact with proteins and glycoproteins that have monoglucosylated N-glycans. The CRT/CNX cycle promotes correct folding, inhibits aggregation of folding intermediates, blocks premature oligimerization, regulates ER degradation, and provides quality control by preventing incompletely folded glycoproteins from exiting to the Golgi complex.
 
品牌介绍
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