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Enzolifesciences/AT1 receptor (extracellular) polyclonal antibody/BML-SA608-0050/50µl
Enzolifesciences/AT1 receptor (extracellular) polyclonal antibody/BML-SA608-0050/50µl
商品编号:
BML-SA608-0050
品牌:
enzolifesciences
市场价:
¥7260.00
美元价:
4356.00
产品分类:
外泌体研究
公司分类:
exosome_research
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Specification:
Alternative Name: | Angiotensin II receptor type 1 |
Host: | Rabbit |
Immunogen: | Synthetic peptide corresponding to aa 4-18 of human AT1. |
UniProt ID: | P30556 |
Species reactivity: | Human, Mouse, Rat |
Applications: | Flow Cytometry, ICC, WB |
Blocking Peptide: | Control peptide is included |
Formulation: | Lyophilized from PBS, pH 7.4, 1% BSA and 0.025% sodium azide. |
Reconstitution: | Reconstitute antibody with either 50µl or 200µl of distilled water depending upon the package size purchased. Reconstitute control peptide with 100µl distilled water. |
Shipping: | Shipped on Blue Ice |
Long Term Storage: | -20°C |
Scientific Background: | Angiotensin II receptor type 1 or AT1 is one of the receptors that binds the octapeptide hormone Angiotensin II (Ang II). Ang II has a central role in cardiovascular homeostasis by regulating vasoconstriction, renal Na and water re-adsorption. In addition, it induces cell growth and proliferation and has pro-inflammatory effects. Most of the physiological actions of Ang II are mediated by AT1 a member of the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. The AT1 receptor is coupled to a Gq/11 protein that activates phospholipase C (PLC) and leads to production of IP3 and intracellular Ca2+ mobilization. In addition to the rapid actions mediated by IP3 and Ca2+ signalling, the AT1 receptor elicits other signalling responses including activation of the MAPK and Jak/STAT. Together, these signaling pathways mediate most of Ang II cellular responses that include, control of hormone secretion, regulation of cell growth and apoptosis, regulation of ion channels activation and cell migration. |
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Company Profile
Name:Enzo Life SciencesCategory:Corporation/Limited Liability CompanyTrade Category: ManufacturerRegistered Time: 1996Registered Capital: Above US$100 MillionLegal Representative:Employees:Address: TaksimWebsite: http://www.enzolifesciences.comProduct/Service: chemicals
Our breadth of scientific expertise coupled with unique technology platforms give us the flexibility to drive innovation throughout the entire research continuum. From life sciences research discovery efforts, through drug development, and into clinical research, our comprehensive range of products are designed to support your goals. When a standard catalog product does not meet your needs, talk to us about custom solutions; we can help
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